I'm really interested in seeing how much these types of smart glasses are going to help visually impaired people. I don't see that mentioned in this article, I'm hopeful these things are another step for better accessibility.
These are interesting, but certainly not at the same level:
Disclaimer: not a doctor (obviously), ask someone who is qualified, but this is what the ID doctor told me:
Lyme is a bacterial infection, and can be cured with antibiotics. Once the bacteria is gone, you no longer have Lyme disease.
However, there is a lot of misinformation about Lyme online. Some people think Lyme is a chronic, incurable disease, which they call "chronic lyme". Often, when a celebrity tells people they have lyme disease, this is what they mean. Chronic lyme is not a real thing - it is a diagnosis given to wealthy people by unqualified conmen or unscrupulous doctors in response to vague, hard to pin symptoms
The late stage of lyme disease is painful. Like "I think I'm dying" painful. It does have a range of symptoms, but those show up like 3 to 6 weeks after the initial infection.
A lot of people claiming chronic lyme disease don't remember this stage.
Lyme disease does cause a range of problems if left untreated. But not before the "I think I'm dying" stage. It's basically impossible for someone, especially with a lot of wealth, to get lyme disease and not have it caught early on.
Consider the OP's story. They tried to not treat it but ended up thinking "OMG, I think I have meningitis and I'm going to die!".
Lyme can kill, but it rarely does. Partially because before it gets to that point it drives people to seek medical attention.
This was an interesting, very long, read! They say of those 25,000 daily trips, most shifted to cycling, walking and public transport, and some moved to other bridges. And then another 9,000 or so were replaced by alternatives that were just better... people tried new transport modes and often found they were better. They do say the closure has created genuine hardship for specific groups.
I don't really buy it. I live in the area, and what happened is that traffic increased dramatically everywhere but Barnes, which is where Hammersmith bridge is. People in Barnes generally love it, as you can read in the author's tone.
London in general has a terrible problem of car commuters who travel 1-2 hours across the city every day. They're going to take whatever route necessary to do it.
“We think that, by modulating cerebrospinal fluid pressure and reducing intracranial venous sinuses compression, these drugs produce a decrease in the release of calcitonin gene-related peptide (CGRP), a key migraine-promoting peptide”, Dr Braca explained. “That would pose intracranial pressure control as a brand-new, pharmacologically targetable pathway.”
I'm not sure I understand what that means, but I wonder if this would work for people who are not obese?
Anecdotes are not data, however I used to have one or more severe migraine headaches weekly. Debilitating migraines. I suffered pretty high blood pressure (which has a very direct relationship with cerebrospinal fluid pressure, which is why I mention this), but aside from that am very healthy and physically fit, exercise regularly, and so on.
I started medication to treat the BP -- telmisartan and amlodipine -- and my BP dropped from 150+/120+ to 115/80. The migraines completely disappeared. I still infrequently get the visual aura that would traditionally precede a migraine, but nothing follows. I haven't had a migraine in the years I've had my BP under control.
Candesartan is actually one of the most used medications for migraine prophylaxis, also for people with normal BP. Your doc might have chosen the med for that reason. Though it's widely used for BP even in people without migraines.
I've had the auras at least since a teenager, but not headaches. Thought is was completely normal, 'til a neurologist said No and that I has having vestibular migraines. Blood pressure was always on the low side of normal.
Family history of migraines and seizures, which some hypothesize have the same root causes. Would be interesting to see GLP-1 tests on epilepsy.
They are positing that the GLP-1 agonist acts mechanistically to modulate CGRP release. But CGRP involvement in migraine is itself only one potential mechanism that causes migraine. I would like to know whether the subjects who responded to the GLP-1 therapy were also responsive to CGRP monoclonal antibody therapy.
My wife has chronic migraines which are successfully mitigated by rimegepant (gepants are CGRP antagonists), and didn't have any particular change in headaches from GLP-1.
What has helped, interestingly, is supplemented creatine HCl (she went with hcl because it's absorbed substantially faster than monohydrate). We've learned that depletion of neural ATP levels can result in an energy crisis which results in cortical spreading depression, which stimulates the release of CGRP. (https://www.sciencedirect.com/topics/neuroscience/spreading-...)
She's found that a) daily supplementation of creatine has reduced her headache days, and b) an immediate dose of creatine upon onset of a headache frequently aborts or mitigates it. Her need for the gepants has dropped to a tiny fraction of what it was prior to starting creatine.
She's tried everything under the sun, had all the scans, tried all the meds and procedures, and creatine and gepants are the only things she's found that have worked. She's not a placebo responder, and hasn't responded to about a zillion other therapies, so we're pretty sure it's not just placebo effect.
I wonder why would they include GitHub stars as comparison point. Not only it is useless, it will mostly be wrong unless dynamically generated and updated.
It does indicate interest in the product from developers, which is helpful to know for smaller OSS projects because it means that people might be able to assist with development and it reduces the likelihood of the project being abandoned when the OG dev moves on.
The Florentine Diamond enjoyed centuries of adventure, a slew of noble owners, and a position of prestige, before it went missing for what is likely the final time.
Whether its adventure covertly continues today or whether it was lost forever, the Florentine diamond—in its massive, multi-faceted gleaming yellow form—is unlikely to ever be publicly seen again.
These are interesting, but certainly not at the same level:
https://www.theverge.com/news/802905/eye-implant-smart-glass...
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