I would uninstall my ad blocking extensions if, and this is a big if, advertisers wouldn't abuse their privilege for me to see their ad. How do they abuse it? By authoring blinking and moving ads that are unbelievably annoying. Everyone once in a while I disable AdBlock, only to flee back to turn it on within a few hours. I'm sorry, but WTF are they smoking?
I use Opera's content-blocking function, which allows me to nuke just a specific ad, or a specific part of a page. If something truly incenses me, I kill it. I think this is how ad blocking should work in general, given that most ads are benign.