That depends on the nature of the genetic disease.
If the original gene produces a protein that actively causes an issue in the body, versus if the gene produces a broken protein that simply fails to do its job.
In the first case, a partial replacement means that the original active protein continues to cause the disease.
In the second case, a partial replacement means that the repaired protein begins expressing itself.
In either case, there may or may not be a linear correlation between the percentage of fixed proteins and the severity of the disease, and that relationship probably isn't well understood in most disease cases, but a partial replacement is likely much more beneficial in the second case, rather than the first.
That is why these initial test are done on chemo patients, so that we can isolate testing of the method of treatment without needed to know what amount of the original tissue needs to be replaced.
There is still a long complicated road ahead. Not a lot of organs get fully replaced in other procedures.
If the original gene produces a protein that actively causes an issue in the body, versus if the gene produces a broken protein that simply fails to do its job.
In the first case, a partial replacement means that the original active protein continues to cause the disease.
In the second case, a partial replacement means that the repaired protein begins expressing itself.
In either case, there may or may not be a linear correlation between the percentage of fixed proteins and the severity of the disease, and that relationship probably isn't well understood in most disease cases, but a partial replacement is likely much more beneficial in the second case, rather than the first.
That is why these initial test are done on chemo patients, so that we can isolate testing of the method of treatment without needed to know what amount of the original tissue needs to be replaced.
There is still a long complicated road ahead. Not a lot of organs get fully replaced in other procedures.