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Yes, this 100%. Back when I started my PhD program in biophysics, the exact opposite was stated: "if you can determine the 3D structure of the protein that causes a disease, you can target it with a drug.". I wasted decades believing that paradigm because really smart people kept repeating it.

unfortunately there is no clear next step for the disease biology part of the study, as far as I can tell, except to collect enormous amounts of high quality data about diseases, typically one or a few at a time, and hope you get lucky finding something (IE, serendipity is just as important as intelligence).



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