I like pylons a lot and I am using it for few projects, but I hate dependecy on many libraries, things get complicated this way very soon. For smaller sites I recommend web2py - it is one package and it is very straightforward and easy although Pylons seems to be more flexible.
dependencies are taken care of by pylons once it gets installed. I like that Ben made it this way because many of these dependencies can be reused in other projects.
