A little addendum (for posterity as this is now an old article post)
• RosettaFold came out in academic paper form as well as open-source github repo slightly prior to AlphaFold. Was AlphaFold's decision to open up motivated by RosettaFold's publishing / opening-up activity? So I feel that the extent of AF's altruism in this (while high) deserves some scrutiny, as perhaps it falls short of the extent that several of us commenting interpreted a couple days ago.
• While RosettaFold allows online execution to the best of their spec, they currently have a backlog queue of ~3000 jobs going back to mid-July. This is telling about the processing power required for folding. AlphaFold has access to a lot of processing power (even if it could ultimately & reasonably end up being on a charge-per-job basis).
• RosettaFold came out in academic paper form as well as open-source github repo slightly prior to AlphaFold. Was AlphaFold's decision to open up motivated by RosettaFold's publishing / opening-up activity? So I feel that the extent of AF's altruism in this (while high) deserves some scrutiny, as perhaps it falls short of the extent that several of us commenting interpreted a couple days ago.
• While RosettaFold allows online execution to the best of their spec, they currently have a backlog queue of ~3000 jobs going back to mid-July. This is telling about the processing power required for folding. AlphaFold has access to a lot of processing power (even if it could ultimately & reasonably end up being on a charge-per-job basis).