Lodish (a then popular cell biology book) and Lehninger (a 1500 page biochem tome) are substantial books. 101 courses would cover the first 5-9 chapters of 25. Reading back to back and understanding all of it puts you at the top of the best students in biology in the world.

I was lucky, I genuinely loved reading them. I think I went through them both once every time I had a bad breakup lol.