Comically low transaction rate, obscenely high power consumption, extreme concentration of BTC holdings in the hands of a small number of people (and companies who have very little influence of global politics), arbitrary growth rate and cap with no correspondence to economic growth, extreme volatility , inconsequentially small use for legal trade, but above all the complete and utter disinterest in it as a reserve currency outside a small echo chamber that has far more BTC to sell than involvement in international trade.
Fortnite Bucks, Mt Gox trading cards, skulls of adult humans and guano also "have the potential to become the world's reserve currency", but it seems unreasonable to put the burden on proof on the people arguing that they won't be.