Yet choosing between the two is not difficult: Nvidia provides me with real performance (stuff I gladly pay for), whereas NixOS provides me with "just" some convenience during installation. NixOS is a cool idea that might have worked incredibly well until about a decade ago, but the world has moved on and we have GPUs now which bring new headaches.
It's more doable on NixOS than on most distros, but the real problem is you're trying to run out-of-tree code. The world isn't going to stop for you (or for all the android devices) so it becomes mainline or GTFO. On reflection I think this is a good thing, despite it meaning I can't play with nvidia things. AMD APUs are good enough these days.
I think it's perfectly possible to use it, you'll just have to do some of the work yourself. The linked jetpack module seems to demonstrate that. Of course, if it's just a few utilities you need you might be able to `patchelf` most of them yourself.
According to the link Nvidia themselves have left the jetson behind, and from memory and a quick search it doesn't look like any other distros support it either.
You can load that support through a NixOS module, though. That's the case for every ARM-based NixOS system to my knowledge, from Apple Silicon to my Rockchip home server.
I think that's going to be very painful though, because Nvidia provides binaries for cuda, cudnn, etc. that depend on one version of libc, whereas NixOS depends on another version of libc.
