In my experience it won't work until you approve it, and even then the messaging Chrome uses here is really obtuse and makes it come off as malicious. A lot of people were initially put off by a recent Reddit Enhancement Suite update that asked the same thing, but all it was doing was trying to access full-sized images posted to the site from their native URLs so you didn't have to click into each one. Not sure if this is always 100% of the case regarding updates, though.