Again, I've had two 4k monitors on Linux for about ten years, and it has worked well the whole time. Back then I used "gnome tweak" to increase the size of widgets etc. Nowadays its built into mate, cinnamon, etc.

What issues? I’m running Mint on a 4k monitor and haven’t had any issues in years

Mixed and fractional scaling both mostly don't work (not complaining, but those a common for people with laptops and external displays).