There are quite a number of interesting LGBT projects happening in the valley. My favourite is my cab service when I'm in town (I prefer this to a usual cab late at night as a solo female traveller): http://www.yelp.com/biz/homobiles-san-francisco. If you'd like to hear some genuine discrimination stories order a cab here sometime, they are unbelievably friendly and happy to discuss why this service exists. There's an unpublished NPR interview out there also, not sure if it's made it to the airwaves.