It already exists because we built it. :P

http://tenderapp.com/

Knowledge base, issue management, development ticket tracker integration, auto-replies, templated responses, etc. We had/have a lot of the same issues I know other small businesses have, so we built a tool to fix it.

Feedback welcome, of course. We eat our own dog food, so file anything you find/any suggestions on http://help.tenderapp.com/

That's great. The email integration is nice and the UI looks slick.

I am interested in build a system of this as well. Drop me a line if somebody want to start brain storm about it.

I'd drop you a line but your profile doesn't have contact info in it. My email is idoh@idoh.com if you want to ping me, I'd love to see what can be done to address this problem.

I really like the media temple kb and support system.