There certainly are USB use cases which Dropbox flat-out doesn't account for.
At one point during the setup of my new gaming PC, I somehow hosed things to the point where I couldn't install Windows (motherboard BIOS update, maybe?). I was getting driver detection failures during the install process, my peripherals (keyboard + mouse) wouldn't work, no NIC functionality, my CD drive was unusable. I ran out to Walmart at 1AM to buy a 16GB USB drive/16GB SD card, tethered my phone (my only functional computer at the time) to my PC, downloaded the required ISO to my phone's new SD card, moved the ISO to a USB via a live instance of Ubuntu running off of another USB, and installed Windows via USB (and things magically worked from there).
At one point during the setup of my new gaming PC, I somehow hosed things to the point where I couldn't install Windows (motherboard BIOS update, maybe?). I was getting driver detection failures during the install process, my peripherals (keyboard + mouse) wouldn't work, no NIC functionality, my CD drive was unusable. I ran out to Walmart at 1AM to buy a 16GB USB drive/16GB SD card, tethered my phone (my only functional computer at the time) to my PC, downloaded the required ISO to my phone's new SD card, moved the ISO to a USB via a live instance of Ubuntu running off of another USB, and installed Windows via USB (and things magically worked from there).
Dropbox is fantastic, but USBs aren't dead.